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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff8b3843fb69cf5b3db02d1effdc01a4660ad15d31c061715038a0facb90e5c' 
  AND token = 'mmypIqec+6TzBasRtODSFLYdPTgL0uUAsJueE5H/nKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}