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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795beb30485db93554c09ff065bba41d0d8885a540a7ce531fc5d5ea8986f934' 
  AND token = 'Rvpy0RDrs+xIAHOhjlx1y88zMpjQmF8A5tBVu0rpcTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}