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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f89dd45c19d56d6a667022f515cea0e011a6f64c5e6a323a3f326ba18eec729' 
  AND token = 'EdeizkdlnqRu1KiGr8jBuvAQLwC2JlrbDvHm5BcQ8jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}