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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a89b6edbf7ddd6d18206f492fac5d650e95343e8d0e4de524352a739b0aa01' 
  AND token = 'jqdgk/RhTSwfU3CV7g97BaBWZlu0R12mLEz1uXy33EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}