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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2edc262cec27392195f63337196829ec5871733d1a370162de608c6c27258c' 
  AND token = 'Cp8HeuJfsp7H6ukPYymQ9Q5yXSFD3MAPjJVAFRNwH/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}