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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a89d0d93529b6f86d066b123b77221805a2d1d739b6686cb31ae2037cca702' 
  AND token = 'jwyBIPr6xd9rBzmqoMcwwGF/hY0Zly9wOUO9OVcql3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}