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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42850f207337c2e20309c4fe87414d7cdfde3736e73899f5b976c3f870ce72e3' 
  AND token = 'tPmiJuxJtPWf+lGTgkxwH4hNOk4TwlVH/f7VVfN/Kb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}