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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f272921542fb75bbd176f5001ce8f9a0d3897e2a4581c409b54fc7e177534599' 
  AND token = 'PdKTcAMXlYi2yPYZh5Zgq/oemwhXA0uINnHfybhNEuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}