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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc88efa21eb116e86ca70ad3f8c6a0001638b9abbfd895d23b2da54cedbc2bf' 
  AND token = 'NE2byL7FDY+iiO2+Yv8NbtczcoP0LijZ6a5GxOrYVpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}