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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '569ec117bb1b26458d0c580993d1c740bae55da19b7b64e129197016082ac50f' 
  AND token = 'uEXQRG7fRz90J7yc3MCMyXbHBl27eFJsq1GZde3+ngM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}