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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29fc2859da354da75b2a38467b2d87b439221bf2fc43bda30c7904f55e29a3d0' 
  AND token = 'MxYnuXx0c7WrMmPPmHevrgugIKSW6tyWsojGgO2jhlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}