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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df1e06c05417017f40d71397ac2b4a532fda7b8d58eaeae35f0cc85fe524e16' 
  AND token = 'Iq2ojaTKgrgzhXXU5/d2MzQ3u3NHyO2LhAaEJ4PFF0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}