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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2d666b15275d1189caeb452d40adf4ac7a3bdd3e1f17769d5e7befaf5424ff' 
  AND token = 'GLuv8Wx94HmgRiXK5KuccMHOAep/0Q4ImVAhV4v00jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}