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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceccbd41a42a9f56f932c6d5ee5def55bf0c04374769315d96df5dfac9cfc632' 
  AND token = 'uOoSme8TKL4X7b0dF3KifFn1rSk9W+xK2nER3BDL8Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}