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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63324b67a1e256abdf1a41a7faa5e6ed179f500f8c4b7062a8d56b76d8cd3347' 
  AND token = 'QQxYoVli7/r4gLaMsye2tD+dBDKSZG/Az5t1XPBuAkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}