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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001c20b033f0f24dd0c620c6da435356ea06462cafed2887466697b0bc225e00' 
  AND token = 'l2JLqB1LQhKDyrNq/4z2+2odE7Bt37wK6YBIQ/WQCgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}