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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6d49f2c097cc73313f542f5cc1e8cfc1f11002e43545549009e2487f237fc9f' 
  AND token = 'KpZe1/WKCTVoDZDWs8BXb9FACl2dRn4Kr232aJNSrRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}