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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8343afbc6e81f36134b020128348fb2356c991e3cbd13cb785603243d2d487f8' 
  AND token = 'iwDZikBJCk0ooGArnah/RX2C6tTK2gm5dG8FCXGx9Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}