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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2bbef78c58dba584a18ca6bb3f091165b15b79012dc8007fc0e532a63873323' 
  AND token = 'PqC6WE3NBPU5VdqnFl7supoAgfCE5X3OFAzp7L+NxY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}