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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3686382898af9fada31c02041f3ce29e183e15259f4e2e3d0daa0af3e92512e7' 
  AND token = 'A1YO3PXHHeBLYYbt1nFDn6mujDpylmHY8eRhWU7VAh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}