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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c3348b42be9665fae98630dca7572e992bf4b8c7a37b8d280a795c6c4ec0e4' 
  AND token = 'j3i5StMzs/9bIUt53WOua7bK+A1Qsv4wNb5oGlFj3tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}