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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b8089e5f10395fb316de5b7b1fbdb349e7f963f08fcf6130dd565f29edd6d0' 
  AND token = 'Po14tIi/pk4cRKkrYVtz/83yLThjlugpT0ZBej7yuHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}