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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c24a3d16245141a9169e377ebf2ee2bf9dba169e046772e0b2501051945caa' 
  AND token = 'sakJ/7V4rFx+ICXrl2Q0MTta/9hwa/TIWe6TP9/LPG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}