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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e60d043847463e47496b33324098c8d908f31e1979ccb183eb42885855351a43' 
  AND token = 'ydLmi3h+hRCOA3zxSR4d2N95ZWWl9rwzaqi/vAuUvkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}