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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7065173c0a4c6583fb0f8af3013626c18cbf737d20ff049116286b4a0b8e8d' 
  AND token = 'h9xcbfCDIP7XKzNud2aTm5bJuaxSbdcR++IsqZWoGfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}