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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0b4c0a73e81b0595f3ae9a7386c8ef46d63375b3c50e28132569f5cb28bb61' 
  AND token = '3XKSb2IIaHa+Br4yKKlebPvREoM7Iod4GaVezuLTIZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}