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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595a4a229fc74dbc5c495abb79fbd5db8961436fa21a3a460ac80da8a0a06317' 
  AND token = 'kzh8N8H/oLdf1ysYnRPZQKIji252uSQooL396w6YLkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}