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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e027f48ab20e7df596a7b3395a27f50b17d5b5d30e91337beee72eac0c895d5' 
  AND token = 'if7TL9AktVofXeSqJsHYTc2r/WR3HP6zXx8ZW9i9lBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}