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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d5e9f1b84636605e40c3136c058e2064b0ba297e6312e0724cf33b5eedde79' 
  AND token = '2l9CbKIw3JsvqcEnTW/LvY2Fvq8oT0vxQ21aObv/Ndc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}