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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8de3441f2e0a878b453afa2d995bc3ee0f527f8f0b6daf9f35732f7dd2ed2e' 
  AND token = '2jOIoEIVWix33bpZNk1Xj2/I3KehL7iLRkomFPsEGsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}