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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5030127ded40a33e7e4231c8fa7509e0fdeac90dfedc0b4ecd94bacb370233' 
  AND token = 'Nq++4vSvaFVYV3up9q2HqCuaWSPBJLWg0MeXd4MlaAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}