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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dec29d1c85067b64abce0a711f6e582a6759e3fabafffaeb4f5b0dea1fbfa16' 
  AND token = 'QSRMafs/RJd5TDv80Gler/uJE6ZvBqfxt0swT48zrdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}