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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d63ae4d35cd794f25c41d5ea83b70a01d49f39b34b65932e14d83067544454' 
  AND token = 'jNwb0WPNtBTS4Q2dhRP6PQinkiXRvpqazTCA8DHEuz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}