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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27dc41f8a3dc59dce1a8b281531ca04ef12af1f53694367844cf9fd4202a50f' 
  AND token = 't9ZHt7qcqIhCvuNbV5C3R2VFImVrg+csNnESUP/+P9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}