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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26cf1aa93fd80e0196f46850c20246e5cc9b516d6893e62b447f02b9cf17b2b5' 
  AND token = 'b3sb5/5e1tIVjUsgNYYPntTQy18PvWCMsfj1Du39JzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}