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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d2cc21c5b4a703b35c1da18499ed6b955d352d6955415cb0abf5aee115ff91' 
  AND token = 'zQZF94USi7NJ7PcqnqUOnYC8s6VDEcQkwWXj7p2rqvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}