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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51eb2a78ab6c2186718594c550d3ec0cd99a28d1d6d698a80ac585e1cad8ed88' 
  AND token = 'SemwV6a5u1YFBuUHKEafT64r2iKkk3WcaffZeTu1LJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}