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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cbb820376b801a1f58b84b74f7d79de0ac809c1fd5f2509a51e2b3b65a65e43' 
  AND token = 'W0vwVkIZaK/bRy6miqF9z2iHDYP4Xnm0qAObHtI2auw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}