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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd37cd938de0ca395dc77ddbf6488c5cf3ad2f4b0a99662c9468e05801f7a4a3' 
  AND token = 'RO+kCTp0kFkw4ZLt3zGIoQiWV1NG/zSstGH6+2pm1AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}