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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c85272b0f00584cfc8cf332ce0a35341501a0712b38cc103cac6aa9e7dcc4e3' 
  AND token = '+7vFeyM7ix0WFIotM0zw61t0/2aZWWbkL2xbLw25Kjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}