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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003e134ac77932f8e0c49b1641719d6af5db2a0c9beecc62a240c13182c5001a' 
  AND token = '+X8aExw6FC8tSvBlxC9Q5HfRu5hN+hNXTsdsnDY9SWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}