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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb27d7752ff908609f09686877ffe1307fe4d49062a8b5e5906ad003ce9ac4c7' 
  AND token = 'AMfKLX+qJewEa7dHjAVkiwfcCJGJ44lNmFG2G+cfIKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}