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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c975493a1ad3b3564b7a8f7fed3240ce56eb21256a63e79317f9245174ddb4a' 
  AND token = 'WEb6y5cqyuQ2KvHTtR2UIxNhNI6vlX6BK2sCYzfwckQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}