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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51013415b3457be1f0d8499b1bbb13e758b341f743b010b39561b6d2740cbcad' 
  AND token = 'bMZJIc/wWKaZbrZnrBubKEo8Rv7YQisv8Vx8lSu1a5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}