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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb39b0653c9eee969d3705291b4afd3f8c9bcf047d736514d59b128b22ae98cf' 
  AND token = 'pJ/yCrk8pqMQ/xETVGyM7s6qG0SGlnUHqP68SwJs0Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}