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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bc61249a86c16a5c16f74e18ac7060ebc62ce9083f4307baa413842ffe61289' 
  AND token = '9P+IBnm4vW4F+fI/5gjTMW+lVsTHJxcj8l4dFFrnARQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}