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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2e44e9caeef4a4c3791e39a6efc708909dc362c29a55e12d6d023d1375a209' 
  AND token = 'OZkcsHPoSTMN9wHOrn1ycTdxpEjJjwpxHBXPEctewoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}