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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b1da58baac366909d52b7bd220295270d4dad306aa41315ee90749f67a6189' 
  AND token = 'U5j578IBaGb6p3VAZCIPJhx5SUaUPwbNA3iKW7/jfjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}