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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906c90f0768460b5e42902df147d4dd81921541db8e8151df4dca7a6ab2e336b' 
  AND token = 'Tq0vOQm+VXlyPnP6DFplE69Lz5WiXySf2wD8Ci7gP/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}