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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1016c340449683b95a08a3697c22e042761ef1d5fc435a8c15d1369535911a' 
  AND token = 'ISm5VT7/XtkkKK8BqR08tBJIVL8/IzTu6uwwr2yXNsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}